Sorry about the Edelbrock carb--I assume it's one of the Carter Clones, not one of their discontinued Q-Jet versions. You'll need to tune the ignition advance for reduced centrifugal and vacuum advance, the "fast burn" chambers won't need or want as much advance as the crappy old heads require.
If you use guideplates, you MUST buy hardened pushrods. Self-aligning rockers won't be a problem though.
If they were my heads, I'd pull them apart, run a straightedge across them looking for warpage. I'd look for guide wear, seat wear, valve-tip and valve stem wear, etc. I'd lap the valves/seats with 400 grit lapping compound, check the castings for cracks. Look over the valve springs with a proper Carpenter's square. Then put the whole works together with fresh valve seals and lube on the valve stems.
If you have to haul them to a machine shop for "serious" work, things are going to get more expensive than I'd be comfortable with. By the time you pay for a proper valve job with guides, plane the deck, trim the guides for high-lift camshaft, etc; you might as well buy aluminum heads.
Or, for that matter, I have a pair of EngineQuest iron castings; Vortec chamber and ports but the old-style 6-bolt intake manifold flange pattern. Zero miles on castings and valves/springs/seals, etc. $600 plus shipping. Given that these are iron castings, shipping will be pricy.--I haven't looked, but I suppose $75-ish. I bought 'em, then went with aluminum Trick Flow heads for my project.