There's not a budget intake manifold upgrade for the Vortec motors, and the factory manifold can support 450 hp.
If you can weld, doing your own exhaust is a good, cheap upgrade. Probably the most bang for the buck. If you can't weld, the price jumps, but it's still worth doing.
A cam costs the same no matter how wild you want to get. The price only jumps when you have to upgrade everything else. The thing to watch out for is the most popular cams command a premium, and there's another manufacturer out there somewhere who will sell you similar specs for less. If you want a budget upgrade, put Elgin 1.6 rockers on your stock cam. Half the price of a new cam, and it'll give you the same specs as a "mild cam upgrade". If you upgrade your cam, absolutely replace your valvesprings. If you drop a valvespring, you trash your motor, and a bigger cam will stress your springs that are already broken and run with a smaller cam. BTDT.
The upgraded MPFIs recently jumped in price - I think I paid $250 for my Suburban's MPFI ten years ago. Now they're $400+. It's still worth it if the truck's worth it. The factory poppets are junk.
If you upgrade the cam, you'll need a tune. An in-person tune is better than a mail order tune.