IF (big IF) he was foot-to-the-floor LONG ENOUGH, I can see the spark plugs getting overheated, leading to detonation/preignition, and then Sudden Terminal Disassembly. NO engine will survive detonation at heavy throttle, or preignition, for long.
(GM used to call light-throttle detonation "The Sound of Economy"--it meant that the ignition timing was maxed-out for a given load and throttle position. Light-throttle detonation is no big deal. Preignition, and medium- or heavy-throttle detonation is DEATH to an engine.)
Boats and longer-term dyno tests sometimes install a colder heat range spark plug before extended (minutes at a time) heavy-throttle use. Under a minute, no problem. Two minutes, maybe no problem. More than two minutes of WFO...be careful with the heat-range.
Flexplates are a known issue with the small-block one-piece seal cranks. But a broken flexplate--while SOUNDING like a rod knock--doesn't drop the oil pressure. OTOH, I can surely understand that a known-weak-design flexplate might crack when running at WFO up a hill.
At high RPM, an oil filter could have the filter media wad-up and block oil flow.
So: First thing I'd do is pull the filter, cut it open, see what the guts look like, and determine if there's metal particles inside.
Next, I'd rip out all eight spark plugs to see if the electrodes are melted. This would be separate from electrodes smashed by contact with a piston, or smashed by debris caught between piston and plug. I'm looking for HEAT damage. But he said he was WFO up a "short" hill, so long term WFO and the associated plug overheating seems unlikely.
Lastly--and very inconveniently--I'd try to inspect the flexplate. Not easy or fun, and I'd do it more out of curiosity than any real hope that it's the problem--due to the lack of oil pressure.
The rebuilder insists that the engine core shipped back to them be "assembled"; but they surely can't cry about oil filters and spark plugs--they'll expect you to throroughly drain the oil and coolant before the carrier picks-up the core.