The frames on these trucks are not as stout as far as torsional twist as one would think.
Ain't that the truth.
In fact, these truck's frames have a problem with what's called 'beam walk'.
An inherent vibration that occurs between 30-40mph (slight) & again between 65-75+mph (pronounced)
GM's aware. ...and they have a 'cure'.
Ballast. Yea. Extra weight.
Their recommendation is to carry a couple of hundred pounds in the box. All the time. WTF?
A more permanent fix is to box the frame.
From the rear cab mount to the shackle mount. Top plates welded to the cross members help, too.
Makes accessing any lines running inside the frame difficult, though.
I've seen some frames that have had trusses added. Alternating vertical & angled steel bars welded inside the leading edges of the frame's C-channel shape.
Easier access to those lines. Less weight than boxing. Easier to fab.