My vote is still for heads, cam and a single plane intake on that 383.
With a 5.13 rear gear and stock V6 4l80E converter my naturally aspirated 383 pulled a 6,200 lbs brick to an 8.48 @ 79 mph in the 1/8. It was not a dead hook either. It was spinning the LT265/75R16s a bit. Ran a 2.15s 60' time. With drag radials it would have cut a sub 2.0s 60' and knocked atleast a couple of tenths off the ET. That is in the ballpark of 500 hp. I was pulling 410 gms/sec of airflow at peak with the smaller 218/228 cam. Horsepower is roughly equal to Mass Airflow in gms/sec multiplied by 1.2. A power robbing 2nd gear dyno was 387 at the wheels through the 4L85E and 10.5" 14-bolt.
ETec200 heads, a 232/244 Lunati Bootlegger cam, Rhoads V-Max lifters adjusted at .014" cold, 1.5:1 roller rockers, a single plane intake and 4" air intake along with decent headers and exhaust would put the HT383 close to 500 hp at 6,000 rpm and have near stock idle quality. With the Rhoads lifters it would have a very flat torque curve and make around 500 ft/lbs at 3,500 rpm too.
Aluminum heads will knock 50 lbs off the front end too and allow for a more aggressive timing advance curve. The timing advance increase helps counter act the larger intake port in low-end torque. The rhoads lifters help counter act the low-end and driveability loss of the bigger cam. Now that I have run the combination myself I will never go back. Its the best of both worlds literally. Like getting the power of a 170cc intake port and small cam on the bottom end and the power of a 200cc head and bigger cam on the top-end. With the idle and fuel mileage of the small headport and cam cruising down the highway.
I bet I knock 3 tenths off my 1/8 mile time with the bigger cam, the larger throttle body and the new converter. 8.20s from a NA L31 based 1-ton Express conversion van will be absolutely hauling ass for what it is. 8.20 1/8 in that brick is roughly a 13 second flat 1/4 mile. The few times it has been on a 1/4 mile track it ran 1.59x the 1/8 mile time in the 1/4. When it had the 350, I went from a stock time of 17.8 to a 15.6 and it still ran the same 1.59x the 1/8 mile time. With drag radials and a day with mineshaft air (negative DA, once raced my Ram in -1,600ft DA!) I am sure I could run a 12.5 in the 1/4.