I have not done a 2wd swap but the Astro vans used the 2wd and 4wd knuckles from the gmt400 trucks in the 2wd and and awd applications respectively. I don't see why 2wd Astro knuckles wouldn't swap to a 2wd truck but again I have not tried it. I have only done the awd astro knuckles to a 4wd gmt400.So, I'm confused. 2wd and 4wd spindles are not the same on gmt400s....