I bought my old ZR2 Blazer with about 150k miles on it and the PO said he replaced the plugs every 50k miles and they were 'all' fresh when I bought it. Well I took one plug wire off and it was a new plug so I didn't worry about them for another 50 or 60k miles.
Well for one plug you have to remove the steering shaft to get it out and apparently the PO didn't want to go through that much effort and 5 out of 6 must have been good enough to qualify as 'all' in his mind. So that one plug I assume was still OEM at 200k miles. The gap was huge and the ground strap was feather thin but it was still running just fine. I was just doing preventative maintenance, I couldn't believe it was still firing, lol.
My '69 Chevelle, SBC/headers, would take 20 minutes to get the 2 back plugs out. Each. 2 universals, 1 long & 1 short extension & a cut down socket.
My '70 Nova, BBC/headers, (smaller car, bigger engine) & I could swap all 8 out in about 1/2 an hour.
Buddy had a '69 Mach-1 with a Drag Pack 428 SCJ/4-gear.
He had to un-bolt the headers, remove the shifter & bell-crank, un-bolt the mounts (engine & trans) remove the driveshaft, undo some wiring, then pull the engine up & about 8" forward just to get to the 2 plugs down by the engine mounts! After the 3rd. or 4th. go-round with that nonsense, he did what every other Mach-1/428 owner did. Drilled a 2" hole in each inner fenderwell. Removing the front wheels to get at those 2 plugs was a lot easier!