Yeah, you can do it....but if the truck is a short wheel base, ya might find it getting unstable on rough sections of highway(those annoying/fun dips and raised sections). The more worn your rear leafs are, the more wobbly you'll feel if it starts "pushing" you down the road. If you engine brake, don't let your engine/tranny do all the work, use your brakes with it, else you'll pop that tranny. Get your rpms to about 2500-3000 before your clutch is fully engaged, that's a good take-off rpm for your engine considering the stock gears are 3.08-3.42 and your engine is healthy. Depending on the tranny, you can save your clutch by rpm-matching while driving, I wouldn't do it until you find out what synchros you have though, some are safe to do it with, others aren't. If I think of anything else, I'll edit this post. Good Luck and be safe, always watch out for people pulling in front of you and don't feel bad if a traffic light on a highway turns red and you blow thru it soon afterwards. It's better you blow thru at a freshly turned red light than jackknife or slide thru it. Take Care man!