Oh, yeah. A poorly-remembered story about my buddy who stuffed a TPI onto an '89 C1500:
He buys a fairly-complete TPI system, sorta like you picture. Builds a "383" using a bottom-feeder Chinese crankshaft. Puts it all together and in the truck. Has "tuning"--a "chip" and maybe a wire harness from one of the Big Names in TPI performance at the time.
First Problem: Scan tool won't talk to the computer. Bang heads on wall for a couple days, finally figure out that the ALDL connector isn't pinned the way the scan tool thinks it should be. I don't know if they used the C1500 ALDL, or the ALDL and harness that came with the TPI. I think they re-pinned the ALDL and then they had no problems with the scan tool after that.
Second Problem: Big Name "tuner" didn't get the tune right. I think they were still sorting the tune when Problem 3 came along.
Third Problem: Likely not related to the TPI. About fifty or a hundred miles into this mess, the crankshaft obliterates the bearings. Engine comes out, he re-grinds the crank, new bearings. I trust this guy, so I expect the engine was cleaned of debris. Vehicle re-assembled, runs and drives, until
Fourth Problem: First time my friend connects the trailer to the truck, he barely gets out of town and the crank eats the bearings again. Engine pulled, has been parked in his garage for a dozen years. C1500 scrapped. He buys a '97 K2500 7.4L in really nice condition.