This is my truck with aftermarket keys, 2" block, 3" body lift, and NON-modified running boards.
Wheels are 16x10 pacers. and tires are 305/70s. Basically the same highth and 1" wider than a 285/75.
This should give you a good perspective because you are asking about pretty much this exact same setup.
Let me know what you think.
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Hard to see but an idea of how much past the fender the tire sticks out
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These next two give you an idea of how the frame looks. Keep in mind that gap guards would really help with the frame above the wheels. (especially rear)
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Sorry for the number of pictures.