When ya say catch can, ya mean the charcoal canister right? If so, then no, the pcv system would run off a 1-way valve. But if your current setup doesn't allow for the stock pcv system, then it won't kill it to not run it. I have it deleted on all my trucks, I just run valve cover breathers in the open holes leftover.
Technically, when you plug it off at the tbi, you're decreasing the air flowing into your engine at idle, but it's only by a little bit and your IAC valve should easily compensate. The pcv system is only active when the throttle plate is closed.