ya ever use it as a highway racer? like 70-90 bursts of speed where you'd need the larger pipe? actually, i guess i should ask if you're planning on using the engine in the 3k+ rpm range alot....now even with the 2" pipe, mine still has amazing torque once it hits 3k, more than it did with the single 3" pipe. For instance, on cruise, it'll pull 35+degree interstate/highway hills without losing any speed in OD. So the 2.25" i would think should be fine man. You're going with magnaflow right? I'm guessing you already have the muffler chosen? If you're doing full length exhaust, and want pressures to be equalized, then go with the di/do....it'll save space underneath and is cheaper. If you dont care about equalizing pressures, or if you prefer the twin muffler look, then go with the (2) si/so.
Whatever you do, it's your truck and I wish you the best of luck. I wanna hear it when you're finished too.