The additive can cause problems with the Gov-loc, doesn't mean it will, but it can. If you hear any chattering noises from back there or it seems like it's engaging/disengaging when you don't expect it to then you should consider changing the lube out.
You can decode most of the RPO's a few different ways.
1. If you've got a friendly dealer nearby you can get a vehicle build report by giving them your VIN. For later trucks like yours, the report is usually detailed with what each RPO means. Older trucks it'll just be the same list of codes the sticker shows, unfortunately.
2. You could run the VIN through a site like compnine, but you'll pay a few bucks for the privilege.
3. You can decode them yourself by searching for each code through an online RPO listing (which is monstrous but easily searched) though just beware that some RPO's get recycled, so you may see a result that doesn't make sense. G80 is one of them, and in other applications (car vs. pickup) it does mean limited slip instead of locker. Some of those codes are just "sales option" codes and won't decode at all. Here's a pretty complete and useful list:
www.someotherplace.com/info/RPO.pdf
Richard