NO!
DO NOT USE AN MSD-5.
You WILL destroy the box. I know this because 1) MSD specifically says not to use a "5" with HEI; and 2) I tried it anyway. Lasted less than a week. Burnt-up the box.
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I patched it up, it ran on the test stand for hours. It's now part of my little red-box stonehenge on a shelf in the shop.
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What you need is an MSD 6 (any version, I guess) and a specific harness adapter. Plug 'n' play--disconnect plastic connector(s) from the coil, plug that into the adapter harness. Plug the harness into the MSD, and use the harness connector to re-connect with the coil. Power and ground for the MSD as usual. Done.
https://www.summitracing.com/parts/msd-8876
I got mine from eBay a thousand years ago, for way less money. No promises on what's available there now.
I then used an MSD 6T with that harness for several years. Eventually the 6T died; took me ten minutes in a parking lot to disconnect the adapter harness and return to non-MSD ignition. Years later, I haven't bothered to re-connect an MSD box...although I probably should since I have a pile of them, (a few of 'em even work) and the adapter harness.
Never noticed a difference in how the truck ran with or without the MSD.