Vortec heads use less timing because of plug position(& swirl), the further it is into the chamber the less advance you need. More timing advance is not always a good thing, more of a necessary evil/loss since combustion works against the rising piston. LS engines are more efficient and need less advance, obviously a much better head design in multiple ways.
I run 200cc heads on 350's in my striped out cars cause they don't need low end for how I set them up, trucks are heavy. Vortecs are a good low-mid range head by design, they also rpm enough for street builds. Support 350-400hp in stock form depending on cam, comp and so on. Straight from a gm engineer that did extensive testing on the heads.