Yes, it will work on our trucks from 96 up. I have the handheld version. Works good on my 97, 5.7L Vortec. I wish I had gotten the CD, laptop version instead though. The handheld version is limited, as to what you can do. The laptop version, is not. Also the handheld version, is locked to what ever truck, you use it on. To use it on another vehicle, you have to set the tune back to factory settings, to unlock it, so it can be used on another vehicle. The laptop version, may come with up to 4 vehicles that you can tune with it, but you need to look at that, to be sureJET’s Dynamic Spectum Tuner claims to accommodate ECUs from 1996.
@df2x4 may have some knowledge of this.
I’ve used JET’s tuner, albeit on a 1998.